Products

Dendritech manufactures and sells ethylenediamine-core poly(amidoamine) (PAMAM) dendrimers in a series of generations with several surface functional groups in diagnostic or technical grades.

Technical grade dendrimers are designed for larger-scale applications and contain higher levels of coproducts, e.g. dimers and lower generations.

Since PAMAM dendrimers are highly viscous oils and are difficult to handle as neat polymers, they are supplied in either methanol or water solutions. We currently sell PAMAM dendrimers with the following surface functional groups:

(a) Primary amine - G0 through G10
(b) Hydroxy - G2 through G7
(c) Carboxylate sodium salt - G0.5 through G7.5 (denoted as half-generations)
(d) C12 hydrophobe G2 through G4-NH2
(e) Technical Grade - G0 through G2 (higher generations available; please inquire)
(f) Mixed amine/hydroxy surface - G2 through G6 (available as special order only)
(g) Succinamic Acid - G(2) through G(6)

Custom Synthesis

Dendritech welcomes inquiries for customized dendrimers to meet your application needs. We have been supplying specifically modified research samples of PAMAM dendrimers for over 20 years, and many have become fully commercial. Dendritech is uniquely qualified to manufacture both research quantities and follow-on commercial quantities in our laboratory and plant facilities. This captive in-house capability insures smooth commercialization of PAMAM dendrimers precisely tailored to your needs.

Technical Grade Dendrimers

Dendritech commercially supplies technical grades of G0 through G2 PAMAM dendrimers. These products combine both the high performance of PAMAM dendrimers with greatly improved economics and are targeted at non-biomedical (industrial) applications. Technical grade products are also commercially supplied with custom surfaces to meet specific customer performance needs. The ability to produce large scaleup quantities of dendrimers from on-site manufacturing is a unique Dendritech strength and we welcome inquiries on pricing and products.

Pricing & Ordering

PAMAM dendrimers are available directly from Dendritech, Inc. with some minimum order quantities required. Smaller research quantities of the following products are available (in methanol solvent only) from Sigma-Aldrich. Aqueous solutions must be ordered directly from Dendritech. All of our PAMAM Dendrimer products have a shelf life of two years from date of manufacture if stored at 5 degrees C or below.

To order from Sigma-Aldrich, call 1-800-558-9160 and order using the catalog numbers listed below. Alternatively, orders can be placed on the web page at www.sigma-aldrich.com (enter the Search Center, type in PAMAM for the Search Text and press the Go button for a full list of the Dendritech products carried by Sigma-Aldrich).


Available Products

Product

Aldrich Catalog Number

PAMAM Dendrimer G0-NH2 41,236-8
PAMAM Dendrimer G1-NH2
41,238-4
PAMAM Dendrimer G2-NH2
41,240-6
PAMAM Dendrimer G3-NH2
41,242-2
PAMAM Dendrimer G4-NH2
41,244-9
PAMAM Dendrimer G5-NH2
53,670-9
PAMAM Dendrimer G6-NH2
53,671-7
PAMAM Dendrimer G7-NH2
53,672-5
PAMAM Dendrimer G8-NH2
53,674-1
PAMAM Dendrimer G9-NH2
53,676-8
PAMAM Dendrimer G10-NH2
53,677-6
PAMAM Dendrimer G0.5 Caboxylate Sodium Salt
41,237-6
PAMAM Dendrimer G1.5 Caboxylate Sodium Salt
41,239-2
PAMAM Dendrimer G2.5 Caboxylate Sodium Salt
41,241-4
PAMAM Dendrimer G3.5 Caboxylate Sodium Salt
41,243-0
PAMAM Dendrimer G4.5 Caboxylate Sodium Salt
47,045-7
PAMAM Dendrimer G5.5 Caboxylate Sodium Salt
53,678-4
PAMAM Dendrimer G6.5 Caboxylate Sodium Salt
53,679-2
PAMAM Dendrimer G7.5 Caboxylate Sodium Salt
53,680-6
PAMAM Dendrimer G2-OH 47,783-4
PAMAM Dendrimer G3-OH
47,784-2
PAMAM Dendrimer G4-OH
47,785-0
PAMAM Dendrimer G5-OH
53,681-4
PAMAM Dendrimer G6-OH
53,682-2
PAMAM Dendrimer G7-OH
53,683-0
PAMAM Dendrimer G2-25% C12 Hydrophobe-
53,684-9
PAMAM Dendrimer G2-50% C12 Hydrophobe-
53,685-7
PAMAM Dendrimer G3-25% C12 Hydrophobe-
53,686-5
PAMAM Dendrimer G3-50% C12 Hydrophobe-
53,687-3
PAMAM Dendrimer G4-25% C12 Hydrophobe-
53,696-2
PAMAM Dendrimer G4-50% C12 Hydrophobe-
53,697-0

PAMAM Dendrimer Succinamic Acid Surface - G(x.0)-SA

Availability

PAMAM Dendrimer G2-SA Succinamic acid
Available from Dendritech
PAMAM Dendrimer G3-SA Succinamic acid
Available from Dendritech
PAMAM Dendrimer G4-SA Succinamic acid
Available from Dendritech
PAMAM Dendrimer G5-SA Succinamic acid
Available from Dendritech
PAMAM Dendrimer G6-SA Succinamic acid
Available from Dendritech
 


* Theoretical calculated properties; not to be used as specifications


How to Order

To order from Dendritech, fax your purchase order to us at (989) 496-2051 or email us. We also accept payment through PayPal; click here for that option.

State the quantity, generation, surface functional group, and solvent (methanol or water). A 10% surcharge is added for water solutions. For orders shipped within the United States and Canada, we add a $75 shipping and handling charge per order. For shipments to outside of the United States and Canada, we add a shipping and handling charge of $150. We accept payment by check, credit card or bank wire transfer.


Dendrimer Price List

(current as of November 1, 2015)

PLEASE NOTE: Price quotes are on an active dendrimer basis (i.e. polymer solids) supplied as solutions in solvent.

Generation
Gx-NH2, Gx-OH*, Gx-C12 or Gx-SA*

Diagnostic
Grade

 

Generation
Gx-COONa

Diagnostic
Grade

0
$32/g
   
1
$83/g
0.5 $92/g
2
$115/g
1.5 $138/g
3
$166/g
2.5 $185/g
4
$231/g
3.5 $277/g
5
$346/g
4.5 $415/g
6
$102/100mg
5.5 $112/100mg
7
$313/100mg
6.5 $344/100mg
8
$677/100mg
7.5 $745/100mg
9
$1,353/100mg
   
10
$2,306/100mg
   

*G2-OH and G2-SA are the lowest generations available in this series.

Please contact Dendritech for prices on larger quantities.


Minimum Quantities

Minimum Quantities of PAMAM Dendrimers that can be ordered directly from Dendritech

Generation

Minimum in Methanol

Minimum in Water

G0-G1 [G0.5]
25g each
3g each
G2-G3 [G1.5-G2.5]
10g each
2g each
G4-G5 [G3.5-G4.5]
2g each
1g each
G6-G7 [G5.5-G6.5]
200mg each
200mg each
G8-G10 [G7.5]
100mg each
100mg each
G0-G2, Technical Grade
100g each
100g each